Spatial segregation of the regulated and constitutive secretory pathways.
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چکیده
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Spatial segregation of the regulated and constitutive secretory pathways
Recent experiments using DNA transfection have shown that secretory proteins in AtT-20 cells are sorted into two biochemically distinct secretory pathways. These two pathways differ in the temporal regulation of exocytosis. Proteins secreted by the regulated pathway are stored in dense-core granules until release is stimulated by secretagogues. In contrast, proteins secreted by the constitutive...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1989
ISSN: 0021-9525,1540-8140
DOI: 10.1083/jcb.109.1.51